Job postings

GSK Computational Chemistry jobs

(Posted 15 May 2016)

Guanglei Cui <guanglei.x.cui@gsk.com> informs us of three openings:

• WD59234 Computational Molecular Design and Data Science
• WD64811 Computational Molecular Design
• one more we're trying to find!

Relay Therapeutics seeking computational chemist

(Posted 15 May 2016)

Pat Walters <pwalters@relaytx.com> writes:

Relay Therapeutics is seeking a highly motivated computational chemist to join our rapidly growing team. This individual will utilize cutting edge computational methods, in conjunction with information generated by a variety of biophysical techniques, to design novel therapeutics targeted to allosteric sites. In this role, the ideal candidate will work as part of a multidisciplinary team to integrate computational and experimental insights and drive drug discovery.

Responsibilities:

• Carry out analyses that combine computational and experimental data to develop testable hypotheses that drive drug discovery programs
• Collaborate with scientists throughout the company to maximize the impact of computational efforts on projects
• Work collaboratively with external computational groups to develop and refine new computational methods
• Ensure effective communication of computational results across departments and teams
• Develop new approaches to streamline and enhance computational workflows

Preferred Qualifications:

• Ph.D. in Computational Chemistry, Computational Biology, Biophysics, or a related discipline
• 1 to 5 years of industrial or postdoctoral experience
• Demonstrated expertise applying wide variety of modern computational chemistry methods
• Demonstrated expertise in structure-based drug design
• In depth knowledge of molecular dynamics and its application to drug discovery
• Facility working in a Unix/Linux environment
• Ability to program in at least 1 modern scripting language (e.g. Python)
• Strong interpersonal and communications skills
• Ability to conduct independent research ​

Mount Sinai - Senior Postdoc / Junior Faculty Position in Computational Biophysics

(Posted 15 May 2016)

6.05.07 SENIOR POSTDOC/JUNIOR FACULTY POSITION IN COMPUTATIONAL BIOPHYSICS, NEW YORK, NEW YORK, USA
A senior postdoc/junior faculty position in computational biophysics is 
available in the Filizola Lab (http://www.filizolalab.org; PI: Prof. Marta 
Filizola) at the Icahn School of Medicine at Mount Sinai, in New York City,
USA. We are seeking highly qualified candidates with an outstanding record 
of research using a variety of computational structural biology tools, 
ranging from molecular modeling, molecular dynamics simulations, free 
energy calculations, and enhanced sampling algorithms to investigate 
molecular mechanisms underlying membrane protein function. 

The ideal candidate would have a Ph.D. degree in Physics, Chemistry, 
Biophysics, Theoretical/Computational Chemistry, or related discipline, 
and a strong background in computer simulations. Proven expertise in 
computational approaches for drug design such as ligand-based and 
structure-based drug design, virtual screening, docking, pharmacophore 
analysis, hit2lead and lead optimization are pluses. Strong communication 
skills, and an ability to both collaborate with peers and train students 
effectively are required. The position is available immediately.
Qualified applicants should send a CV and at least 2 reference names by 
email to Dr. Marta Filizola at marta.filizola#%#mssm.edu. Applications 
will be considered until the position is filled.

Link to full job posting

Vertex - Research Scientist, Computational Chemist / Modeling and Informatics

(Posted 15 May 2016)

• PDF flyer

Postdoctoral position in the Shen lab

(Posted 15 May 2016)

Position: post-doctoral fellows
Projects:
development/implementation of constant pH tools
mechanisms of proton-coupled transporters
Location:
Dept Pharmaceutical Science
Computer-Aided Drug Design Center
University of Maryland School of Pharmacy, Baltimore, MD
Contact:
Dr. Jana Shen (jshen@rx.umaryland.edu<mailto:jshen@rx.umaryland.edu>)
Jana
Jana Shen
Associate Professor
Codirector, Computer-Aided Drug Design Center
Department of Pharmaceutical Sciences
University of Maryland School of Pharmacy
Baltimore, MD
jshen@rx.umaryland.edu<mailto:jshen@rx.umaryland.edu>
(410) 706-4187

Postdoctoral positions at Merck Serono

(Posted 15 May 2016)

From Daniel Kuhn:

• Postdoctoral researcher for predictive models in drug design (PDF)
• Postdoctoral researcher in computational chemistry, molecular dynamics, and FEP (PDF)